DPP10

Across TCGA cell cohorts, DPP10 mutation is significantly associated with the RNA expression of many other genes, with 90 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPP10-associated genes across cancer lineages are OR4X2, FAM71B, and GPR171. Each is linked with DPP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPP10-to-partner and partner-to-DPP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4X2 grouped by DPP10-low versus DPP10-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP10→partner) and Y-score (partner→DPP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.013	+4.369	.006	.008	3	2
LUNG_NSCLC_LUAD	FAM71B →	+0.003	+3.440	<.001	.001	3	2
LUNG_NSCLC_LUAD	GPR171 →	+0.032	+3.315	<.001	<.001	3	2
LUNG_NSCLC_LUAD	OR8D1 →	+0.035	+2.343	.001	.008	3	2
LUNG_NSCLC_LUSC	TMEM239 →	+0.040	+3.584	<.001	.003	3	1
SOFT_TISSUE	IFNA14 →	+0.024	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

OR4X2 by DPP10 expression — SOFT_TISSUE

Explore this box plot interactively →