DPP10

Across TCGA pan-cancer cohorts, DPP10 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of DPP10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DPP10 RNA is repressed in tumor relative to normal tissue. In most cancer types DPP10 is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, COAD, and UCEC are the cancer types where DPP10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DPP10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.478	<.001	12	view →
COAD	Female	II,III,IV	−1.093	<.001	10	view →
UCEC	All	II,III,IV	+1.711	<.001	6	view →
LUAD	Female	All	+0.537	<.001	4	view →
STAD	Male	All	−0.316	.015	4	view →
BRCA	Female	II,III,IV	+0.146	.014	4	view →
THCA	All	II,III,IV	+0.311	.010	3	view →
READ	Female	All	−1.376	<.001	2	view →
CHOL	All	All	+1.150	.003	2	view →
ESCA	All	All	−0.597	.018	1	view →
LIHC	Female	All	+0.325	.047	1	view →
LUSC	Female	III,IV	−0.069	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

DPP10–KIRC

Open the KIRC breakdown →