DPH6

Across TCGA patient cohorts, DPH6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,296 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DPH6-associated genes across cancer lineages are SETD3, CYTH4, and PDE10A. Each is linked with DPH6 in more than 3 cancer types. Because this analysis shows association rather than direction, both DPH6-to-partner and partner-to-DPH6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPH6 versus SETD3 in CCRCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH6→partner) and Y-score (partner→DPH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SETD3 →	+0.380	+0.182	<.001	<.001	3	4
LSCC	CYTH4 →	-0.584	-0.260	<.001	<.001	3	3
CCRCC	PDE10A →	-1.360	-0.202	.002	.003	3	3
LSCC	ARHGAP9 →	-0.635	-0.286	<.001	<.001	3	3
LSCC	ZBP1 →	-0.838	-0.233	<.001	.001	3	3
LSCC	STAT5A →	-0.524	-0.255	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,296 associations by consensus.

DPH6 vs SETD3 — CCRCC

Explore this scatter interactively →