DPH1

Across TCGA patient cohorts, DPH1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,607 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DPH1-associated genes across cancer lineages are PCDH12, DPH2, and KIF2C. Each is linked with DPH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DPH1-to-partner and partner-to-DPH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPH1 versus PCDH12 in CCRCC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH1→partner) and Y-score (partner→DPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PCDH12 →	-0.731	-0.223	<.001	<.001	3	7
LSCC	DPH2 →	+0.575	+0.293	<.001	<.001	3	6
BRCA	KIF2C →	+0.948	+0.239	<.001	<.001	3	6
OV	CXCL12 →	-1.795	-0.410	<.001	<.001	2	6
BRCA	INPP4B →	-1.298	-0.193	<.001	.008	3	5
GBM	PDE1B →	-0.385	-0.184	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,607 associations by consensus.

DPH1 vs PCDH12 — CCRCC

Explore this scatter interactively →