Across TCGA patient cohorts, DPF3 mutation is significantly associated with the RNA expression of many other genes, with 4,696 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPF3-associated genes across cancer lineages are MRPL10, ZSCAN22, and NCKIPSD. Each is linked with DPF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPF3-to-partner and partner-to-DPF3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPF3→partner) and Y-score (partner→DPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL10 →	+0.296	+1.917	.004	<.001	3	3
UCEC	ZSCAN22 →	+0.298	+2.386	<.001	.002	3	3
UCEC	NCKIPSD →	+0.328	+2.436	.002	.001	3	3
SKCM	PIP4K2C →	+0.511	+3.478	.005	.002	3	3
UCEC	ATP6V1D →	+0.415	+2.146	<.001	<.001	3	3
SKCM	PPP1R37 →	+0.459	+2.172	.008	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,696 associations by consensus.

Exploration

DPF3 survival (RNA) · tumor vs normal (RNA) · all DPF3 data types