DPAGT1

Across TCGA patient cohorts, DPAGT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. THYM shows the largest number of these associations.

The most reproducible DPAGT1-associated GO terms across cancer lineages are Meiotic chromosome condensation, Positive regulation of chromosome condensation, and XMP metabolic process. Each is linked with DPAGT1 in more than 26 cancer types. Because this analysis shows association rather than direction, both DPAGT1-to-partner and partner-to-DPAGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic chromosome condensation grouped by DPAGT1-low versus DPAGT1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPAGT1→partner) and Y-score (partner→DPAGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Meiotic chromosome condensation →	+0.112	+0.635	<.001	<.001	3	27
DLBC	Positive regulation of chromosome condensation →	+0.171	+0.876	<.001	<.001	3	27
DLBC	XMP metabolic process →	+0.072	+0.565	<.001	<.001	3	27
DLBC	'de novo' AMP biosynthetic process →	+0.074	+0.516	<.001	<.001	3	25
ACC	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.047	+1.020	<.001	<.001	3	25
THYM	Mitotic G2 DNA damage checkpoint signaling →	+0.053	+0.449	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Meiotic chromosome condensation by DPAGT1 expression — DLBC

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