DPAGT1

Across TCGA patient cohorts, DPAGT1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,341 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DPAGT1-associated genes across cancer lineages are MAPK8, PTGES3, and SPTBN1. Each is linked with DPAGT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPAGT1-to-partner and partner-to-DPAGT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPAGT1 versus MAPK8 in PDAC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPAGT1→partner) and Y-score (partner→DPAGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MAPK8 →	-0.374	-0.691	<.001	<.001	3	3
GBM	PTGES3 →	-0.440	-0.339	<.001	.002	3	3
COAD	SPTBN1 →	-0.617	-0.287	.002	<.001	3	3
GBM	RTN4 →	-0.500	-0.462	<.001	<.001	3	3
PDAC	STRN →	-0.383	-0.739	<.001	<.001	3	3
OV	C2orf42 →	-0.359	-0.326	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,341 associations by consensus.

DPAGT1 vs MAPK8 — PDAC

Explore this scatter interactively →