DPAGT1

Across TCGA cell cohorts, DPAGT1 mutation is significantly associated with the RNA expression of many other genes, with 1,194 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPAGT1-associated genes across cancer lineages are LILRA1, SERPINA12, and SULT6B1. Each is linked with DPAGT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPAGT1-to-partner and partner-to-DPAGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by DPAGT1-low versus DPAGT1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPAGT1→partner) and Y-score (partner→DPAGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LILRA1 →	+0.113	+4.930	<.001	.008	3	2
BREAST	SERPINA12 →	+0.080	+3.657	<.001	.009	3	2
BONE	SULT6B1 →	+0.017	+4.169	<.001	.008	3	1
BONE	TPRX1 →	+0.052	+4.000	<.001	.008	3	1
BONE	VN1R3 →	+0.035	+4.169	<.001	.008	3	1
BONE	TMPRSS11B →	+0.073	+4.307	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,194 associations by consensus.

LILRA1 by DPAGT1 expression — SOFT_TISSUE

Explore this box plot interactively →