DOLPP1

Across TCGA patient cohorts, DOLPP1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,634 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DOLPP1-associated genes across cancer lineages are DYNC2I2, GLE1, and PTGES2. Each is linked with DOLPP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DOLPP1-to-partner and partner-to-DOLPP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOLPP1 versus DYNC2I2 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOLPP1→partner) and Y-score (partner→DOLPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DYNC2I2 →	+0.659	+0.363	<.001	<.001	3	4
OV	GLE1 →	+0.682	+0.362	<.001	<.001	3	4
BRCA	PTGES2 →	+0.685	+0.847	.002	.004	3	4
BRCA	DOLK →	+0.723	+0.959	<.001	<.001	3	4
LSCC	WDR5 →	+0.507	+0.392	.007	.001	3	4
HNSC	NUP188 →	+0.568	+0.318	.006	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,634 associations by consensus.

DOLPP1 vs DYNC2I2 — OV

Explore this scatter interactively →