DOLPP1

Across TCGA cell cohorts, DOLPP1 mutation is significantly associated with the mutation status of many other genes, with 153 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DOLPP1-associated genes across cancer lineages are ZNF283, TK1, and ZNF597. Each is linked with DOLPP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DOLPP1-to-partner and partner-to-DOLPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF283 grouped by DOLPP1-low versus DOLPP1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOLPP1→partner) and Y-score (partner→DOLPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF283 →	+4.736	+5.560	.003	.003	1	1
BLOOD_Leukemia	TK1 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	ZNF597 →	+4.321	+5.285	.005	.005	1	1
BLOOD_Leukemia	B3GNT2 →	+4.321	+5.285	.005	.005	1	1
BLOOD_Leukemia	KBTBD2 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	TADA3 →	+4.000	+5.050	.008	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 153 associations by consensus.

ZNF283 by DOLPP1 expression — BLOOD_Leukemia

Explore this box plot interactively →