Across TCGA patient cohorts, DOK6 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,101 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DOK6-associated proteins across cancer lineages are PRKG1, CNRIP1, and CYGB. Each is linked with DOK6 in more than 7 cancer types. Because this analysis shows association rather than direction, both DOK6-to-partner and partner-to-DOK6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK6→partner) and Y-score (partner→DOK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PRKG1 →	+0.713	+0.477	<.001	<.001	3	8
OV	CNRIP1 →	+0.790	+0.479	<.001	<.001	3	8
OV	CYGB →	+0.684	+0.527	<.001	<.001	3	8
BRCA	OLFML1 →	+1.130	+0.512	<.001	<.001	3	7
OV	CACNA2D1 →	+0.865	+0.681	<.001	<.001	3	7
COAD	DPYSL2 →	+0.409	+0.300	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,101 associations by consensus.

Exploration

DOK6 survival (RNA) · tumor vs normal (RNA) · all DOK6 data types