Across TCGA patient cohorts, DOK6 mutation is significantly associated with the RNA expression of many other genes, with 2,147 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DOK6-associated genes across cancer lineages are TRAJ57, RNU6-1191P, and NDUFA6. Each is linked with DOK6 in more than 2 cancer types. Because this analysis shows association rather than direction, both DOK6-to-partner and partner-to-DOK6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK6→partner) and Y-score (partner→DOK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TRAJ57 →	+1.334	+5.788	<.001	.003	3	3
CESC	RNU6-1191P →	+1.483	+5.103	<.001	.008	3	3
UCEC	NDUFA6 →	+0.450	+2.369	<.001	.003	3	3
UCEC	PRIM1 →	+0.733	+2.354	<.001	<.001	3	3
UCEC	HAUS6P1 →	+0.071	+2.004	.002	.001	3	3
UCEC	EIF4EP2 →	+0.472	+2.338	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,147 associations by consensus.

Exploration

DOK6 survival (RNA) · tumor vs normal (RNA) · all DOK6 data types