Across TCGA cell cohorts, DOK6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,345 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DOK6-associated GO terms across cancer lineages are Axo-dendritic transport, Negative regulation of neurotransmitter uptake, and Dopamine uptake involved in synaptic transmission. Each is linked with DOK6 in more than 4 cancer types. Because this analysis shows association rather than direction, both DOK6-to-partner and partner-to-DOK6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK6→partner) and Y-score (partner→DOK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Axo-dendritic transport →	+0.051	+1.097	.008	.008	3	5
KIDNEY	Negative regulation of neurotransmitter uptake →	+1.014	+0.620	.003	.004	3	5
KIDNEY	Dopamine uptake involved in synaptic transmission →	+1.177	+0.617	<.001	.004	3	5
KIDNEY	Negative regulation of serotonin uptake →	+1.014	+0.620	.003	.004	3	5
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.099	+1.793	.001	.003	3	5
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.101	+1.823	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,345 associations by consensus.

Exploration

DOK6 survival (RNA) · tumor vs normal (RNA) · all DOK6 data types