DOK4

Across TCGA cell cohorts, DOK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,855 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DOK4-associated GO terms across cancer lineages are Fatty acid beta-oxidation, Protein localization to plasma membrane, and Response to epidermal growth factor. Each is linked with DOK4 in more than 10 cancer types. Because this analysis shows association rather than direction, both DOK4-to-partner and partner-to-DOK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation grouped by DOK4-low versus DOK4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK4→partner) and Y-score (partner→DOK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Fatty acid beta-oxidation →	+0.081	+0.959	.001	.003	3	10
PANCREAS	Protein localization to plasma membrane →	+0.053	+1.381	.002	<.001	2	11
STOMACH	Response to epidermal growth factor →	+0.115	+1.893	.006	.006	3	9
LIVER	Positive regulation of lamellipodium morphogenesis →	+0.161	+2.372	.003	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Cellular response to epidermal growth factor stimulus →	+0.146	+1.351	<.001	<.001	3	8
KIDNEY	Equilibrioception →	+2.301	+1.528	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,855 associations by consensus.

Fatty acid beta-oxidation by DOK4 expression — URINARY_TRACT

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