DOCK9-DT

Across TCGA pan-cancer cohorts, DOCK9-DT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated DOCK9-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DOCK9-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated DOCK9-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUAD show a favorable association.

KIRC, LUAD, and THCA are the cancer types where DOCK9-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.709	0.550	<.001	74	view →
LUAD	OS	Tertile	III,IV	0.787	0.459	<.001	67	view →
THCA	OS	Tertile	All	0.972	0.866	.003	49	view →
PAAD	OS	Quartile	All	0.493	0.150	.002	39	view →
MESO	OS	Median	All	0.371	0.206	.004	35	view →
GBM	OS	Quartile	All	0.346	0.582	<.001	30	view →
CHOL	OS	Median	III,IV	1.000	0.286	.008	26	view →
LGG	DFS	Quartile	All	0.672	0.838	<.001	23	view →
COAD	DFS	Tertile	IV	0.641	0.349	.015	17	view →
ESCA	DFS	Tertile	IV	0.692	0.221	.024	16	view →
THYM	DFS	Quartile	All	0.967	0.779	.009	16	view →
OV	OS	Quartile	All	0.901	0.791	.002	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

DOCK9-DT–KIRC (OS)

Open the KIRC breakdown →