DOCK9-AS1

Across TCGA pan-cancer cohorts, DOCK9-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated DOCK9-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher DOCK9-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DOCK9-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and LUAD show a favorable association.

ACC, OV, and UVM are the cancer types where DOCK9-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	III,IV	0.010	0.458	<.001	63	view →
OV	DFS	Median	II,III,IV	0.198	0.118	.005	48	view →
UVM	DFS	Tertile	All	0.241	0.771	.004	45	view →
LUAD	OS	Tertile	III,IV	0.993	0.569	.003	33	view →
ESCA	OS	Median	II,III,IV	0.590	0.353	.013	30	view →
LIHC	OS	Quartile	All	0.892	0.582	.001	28	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	27	view →
UCS	DFS	Tertile	All	0.161	0.529	.027	18	view →
LUSC	DFS	Tertile	III,IV	0.010	0.754	<.001	18	view →
DLBC	OS	Tertile	All	0.551	0.953	.019	18	view →
CHOL	OS	Tertile	II,III,IV	0.024	0.601	.025	18	view →
READ	DFS	Tertile	IV	0.427	0.662	.035	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

DOCK9-AS1–ACC (DFS)

Open the ACC breakdown →