DOCK9-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, DOCK9-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of DOCK9-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where DOCK9-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types DOCK9-AS1 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and CHOL are the cancer types where DOCK9-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DOCK9-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHAllII,III,IV−0.128.0047view →
KIRPFemaleAll−0.149<.0015view →
CHOLAllAll−0.322.0212view →
LIHCFemaleII,III,IV−0.165.0162view →
BRCAAllIII,IV−0.142.0012view →
LUSCFemaleAll−0.091.0092view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

DOCK9-AS1–KICH

Tumor-vs-normal expression box plot for DOCK9-AS1 RNA in KICH.

Open the KICH breakdown →

Exploration