Across TCGA patient cohorts, DOCK8-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,464 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DOCK8-AS1-associated proteins across cancer lineages are PTPN6, STK10, and DOCK8. Each is linked with DOCK8-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DOCK8-AS1-to-partner and partner-to-DOCK8-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK8-AS1→partner) and Y-score (partner→DOCK8-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPN6 →	+0.646	+0.504	<.001	<.001	3	7
UCEC	STK10 →	+0.442	+0.694	<.001	<.001	3	7
GBM	DOCK8 →	+0.565	+0.601	<.001	<.001	3	7
GBM	MYO1F →	+0.621	+0.556	<.001	<.001	3	6
GBM	MYO1G →	+0.606	+0.506	<.001	<.001	3	6
UCEC	NCEH1 →	+0.775	+0.514	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,464 associations by consensus.

Exploration

DOCK8-AS1 survival (RNA) · tumor vs normal (RNA) · all DOCK8-AS1 data types