Across TCGA patient cohorts, DOCK8-AS1 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DOCK8-AS1-associated genes across cancer lineages are MIR1225, RNA5SP414, and RNA5SP411. Each is linked with DOCK8-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DOCK8-AS1-to-partner and partner-to-DOCK8-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK8-AS1→partner) and Y-score (partner→DOCK8-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR1225 →	+0.468	+7.640	<.001	.009	3	2
UCEC	RNA5SP414 →	+0.707	+3.670	.001	.002	3	1
UCEC	RNA5SP411 →	+2.058	+3.715	<.001	.001	3	1
UCEC	RNU6-553P →	+0.615	+3.348	.001	.004	3	1
UCEC	RNU6-431P →	+0.805	+3.938	.003	.002	3	1
UCEC	RNU6-767P →	+0.488	+3.701	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

DOCK8-AS1 survival (RNA) · tumor vs normal (RNA) · all DOCK8-AS1 data types