DOCK11

Across TCGA patient cohorts, DOCK11 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,094 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK11-associated proteins across cancer lineages are ANKRD44, LCP2, and DOCK11_T1352. Each is linked with DOCK11 in more than 7 cancer types. Because this analysis shows association rather than direction, both DOCK11-to-partner and partner-to-DOCK11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK11 versus ANKRD44 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK11→partner) and Y-score (partner→DOCK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+0.520	+1.300	<.001	<.001	3	8
BRCA	LCP2 →	+0.486	+0.819	<.001	<.001	3	8
OV	DOCK11_T1352 →	+1.190	+1.166	.004	.006	3	8
GBM	DOK2 →	+0.770	+0.612	<.001	<.001	3	8
OV	ARHGAP25 →	+1.329	+1.635	.005	.002	3	8
UCEC	WIPF1 →	+0.381	+0.860	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,094 associations by consensus.

DOCK11 vs ANKRD44 — OV

Explore this scatter interactively →