DOCK11

Across TCGA patient cohorts, DOCK11 protein abundance is significantly associated with the RNA expression of many other genes, with 19,727 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK11-associated genes across cancer lineages are IL21R, WIPF1, and SEPTIN6. Each is linked with DOCK11 in more than 9 cancer types. Because this analysis shows association rather than direction, both DOCK11-to-partner and partner-to-DOCK11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK11 versus IL21R in GBM, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK11→partner) and Y-score (partner→DOCK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IL21R →	+1.347	+0.362	<.001	<.001	3	10
OV	WIPF1 →	+1.020	+0.615	<.001	<.001	3	10
OV	SEPTIN6 →	+1.221	+0.701	<.001	<.001	3	10
HNSC	CD72 →	+0.833	+0.300	<.001	<.001	3	10
HNSC	MYO1F →	+0.990	+0.508	<.001	<.001	3	10
LSCC	C1orf162 →	+0.833	+0.369	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,727 associations by consensus.

DOCK11 vs IL21R — GBM

Explore this scatter interactively →