DOCK11

Across TCGA cell cohorts, DOCK11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,970 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DOCK11-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Regulation of angiotensin-activated signaling pathway, and Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. Each is linked with DOCK11 in more than 9 cancer types. Because this analysis shows association rather than direction, both DOCK11-to-partner and partner-to-DOCK11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by DOCK11-low versus DOCK11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK11→partner) and Y-score (partner→DOCK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Post-Golgi vesicle-mediated transport →	+0.056	+1.590	.003	.005	3	10
URINARY_TRACT	Regulation of angiotensin-activated signaling pathway →	+0.185	+1.916	<.001	<.001	3	10
SOFT_TISSUE	Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.079	+1.231	.001	.001	3	9
SOFT_TISSUE	Vesicle budding from membrane →	+0.075	+0.951	<.001	.003	3	8
SOFT_TISSUE	Macroautophagy →	+0.043	+0.898	<.001	.006	3	8
BONE	Negative regulation of transforming growth factor beta receptor signaling pathway →	+0.088	+1.711	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,970 associations by consensus.

Post-Golgi vesicle-mediated transport by DOCK11 expression — BONE

Explore this box plot interactively →