DOCK10

Across TCGA patient cohorts, DOCK10 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,783 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK10-associated proteins across cancer lineages are ARHGAP15_S64, ARHGAP30, and ARHGAP45. Each is linked with DOCK10 in more than 9 cancer types. Because this analysis shows association rather than direction, both DOCK10-to-partner and partner-to-DOCK10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK10 versus ARHGAP15_S64 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK10→partner) and Y-score (partner→DOCK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP15_S64 →	+1.010	+0.818	<.001	<.001	3	10
OV	ARHGAP30 →	+0.739	+1.095	<.001	<.001	3	10
UCEC	ARHGAP45 →	+0.560	+0.769	<.001	<.001	3	10
UCEC	PLEKHO2 →	+0.449	+0.602	<.001	<.001	3	10
HNSC	RCSD1 →	+0.692	+0.902	<.001	<.001	3	10
GBM	SASH3 →	+0.634	+0.879	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,783 associations by consensus.

DOCK10 vs ARHGAP15_S64 — LSCC

Explore this scatter interactively →