DOC2B

Across TCGA cell cohorts, DOC2B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,416 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DOC2B-associated GO terms across cancer lineages are Excitatory postsynaptic potential, DNA-templated transcription initiation, and Cellular response to arsenic-containing substance. Each is linked with DOC2B in more than 5 cancer types. Because this analysis shows association rather than direction, both DOC2B-to-partner and partner-to-DOC2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Excitatory postsynaptic potential grouped by DOC2B-low versus DOC2B-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOC2B→partner) and Y-score (partner→DOC2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Excitatory postsynaptic potential →	-0.083	-0.598	.001	.003	3	6
BONE	DNA-templated transcription initiation →	+0.068	+1.763	<.001	<.001	3	6
BONE	Cellular response to arsenic-containing substance →	+0.109	+1.950	.006	<.001	2	6
LUNG_SCLC	Regulation of proteasomal protein catabolic process →	+0.059	+1.140	<.001	.007	2	6
BONE	Mineralocorticoid metabolic process →	+1.851	+2.232	<.001	<.001	3	5
BONE	Negative regulation of chromatin organization →	+0.157	+1.916	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,416 associations by consensus.

Excitatory postsynaptic potential by DOC2B expression — LUNG_NSCLC_LUAD

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