DNTTIP2

Across TCGA patient cohorts, DNTTIP2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,626 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNTTIP2-associated genes across cancer lineages are ATAD2, LMOD1, and WDR43. Each is linked with DNTTIP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DNTTIP2-to-partner and partner-to-DNTTIP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNTTIP2 versus ATAD2 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNTTIP2→partner) and Y-score (partner→DNTTIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATAD2 →	+1.070	+0.294	<.001	<.001	3	8
OV	LMOD1 →	-1.259	-0.357	<.001	<.001	3	8
HNSC	WDR43 →	+0.958	+0.236	.001	<.001	3	8
BRCA	MSRB3 →	-1.111	-0.263	<.001	<.001	3	8
BRCA	LHFPL6 →	-0.985	-0.286	<.001	<.001	3	8
LSCC	CMSS1 →	+0.718	+0.284	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,626 associations by consensus.

DNTTIP2 vs ATAD2 — BRCA

Explore this scatter interactively →