DNPH1

Across TCGA cell cohorts, DNPH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,948 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNPH1-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Aminoacyl-tRNA metabolism involved in translational fidelity. Each is linked with DNPH1 in more than 12 cancer types. Because this analysis shows association rather than direction, both DNPH1-to-partner and partner-to-DNPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by DNPH1-low versus DNPH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNPH1→partner) and Y-score (partner→DNPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.095	+1.080	.001	.002	3	13
BONE	Electron transport coupled proton transport →	+0.095	+1.080	.001	.002	3	13
URINARY_TRACT	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.135	+1.265	<.001	<.001	3	10
PANCREAS	Methylglyoxal metabolic process →	+0.119	+1.225	<.001	.002	3	10
LUNG_SCLC	U4 snRNA 3'-end processing →	+0.140	+1.102	<.001	.001	3	10
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.146	+1.045	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by DNPH1 expression — BONE

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