DNMT3L-AS1

Across TCGA patient cohorts, DNMT3L-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,785 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DNMT3L-AS1-associated GO terms across cancer lineages are Mitochondrial translation, Mitochondrial gene expression, and Peptidyl-arginine modification. Each is linked with DNMT3L-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DNMT3L-AS1-to-partner and partner-to-DNMT3L-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by DNMT3L-AS1-low versus DNMT3L-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNMT3L-AS1→partner) and Y-score (partner→DNMT3L-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial translation →	+0.040	+0.044	.005	<.001	3	8
STAD	Mitochondrial gene expression →	+0.039	+0.035	.004	<.001	3	7
STAD	Peptidyl-arginine modification →	+0.030	+0.039	<.001	<.001	2	8
HNSC	Regulation of DNA-directed DNA polymerase activity →	+0.062	+0.054	<.001	<.001	3	7
STAD	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.032	+0.035	.008	<.001	3	7
HNSC	Mitochondrial respiratory chain complex assembly →	+0.040	+0.092	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,785 associations by consensus.

Mitochondrial translation by DNMT3L-AS1 expression — STAD

Explore this box plot interactively →