DNM3OS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNM3OS RNA expression is significantly associated with the protein abundance of many other proteins, with 19,306 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DNM3OS-associated proteins across cancer lineages are SGCD, TIMP2, and ZYX. Each is linked with DNM3OS in more than 9 cancer types. Because this analysis shows association rather than direction, both DNM3OS-to-partner and partner-to-DNM3OS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNM3OS versus SGCD in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM3OS→partner) and Y-score (partner→DNM3OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSGCD →+0.898+0.935<.001<.001310
BRCATIMP2 →+0.879+1.402<.001<.001310
UCECZYX →+0.461+0.874<.001<.00139
OVRCN3 →+0.712+1.384<.001<.00139
OVSERPINF1 →+0.972+1.507<.001<.00139
BRCASERPINH1 →+0.583+0.982<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,306 associations by consensus.

DNM3OS vs SGCD — HNSC

Per-sample scatter of DNM3OS vs SGCD in HNSC (Pearson r = 0.38).

Explore this scatter interactively →

Exploration