DNM1P48

Across TCGA patient cohorts, DNM1P48 RNA expression is significantly associated with the mutation status of many other genes, with 4 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible DNM1P48-associated genes across cancer lineages are HRAS, TRIP11, and DNM1P47. Each is linked with DNM1P48 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNM1P48-to-partner and partner-to-DNM1P48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HRAS grouped by DNM1P48-low versus DNM1P48-high in PCPG.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1P48→partner) and Y-score (partner→DNM1P48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	HRAS →	+3.459	+0.021	.009	<.001	3	1
ESCA	TRIP11 →	+4.709	+0.047	.003	<.001	3	1
ESCA	DNM1P47 →	+5.709	+0.071	.001	<.001	3	1
ESCA	BAZ2A →	+6.709	+0.095	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

HRAS by DNM1P48 expression — PCPG

Explore this box plot interactively →