DNM1P47

Across TCGA patient cohorts, DNM1P47 mutation is significantly associated with the RNA expression of many other genes, with 825 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNM1P47-associated genes across cancer lineages are MIR4762, PRAMEF5, and RN7SL248P. Each is linked with DNM1P47 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNM1P47-to-partner and partner-to-DNM1P47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4762 grouped by DNM1P47-low versus DNM1P47-high in THYM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1P47→partner) and Y-score (partner→DNM1P47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	MIR4762 →	+0.566	+4.853	.002	.002	3	2
THYM	PRAMEF5 →	+0.121	+4.350	<.001	.006	3	2
THCA	RN7SL248P →	+0.104	+7.962	<.001	.007	3	2
HNSC	FDX1P2 →	+0.109	+5.368	<.001	.005	3	2
HNSC	RNU6-436P →	+0.408	+5.505	<.001	.004	3	2
BLCA	RNU6-984P →	+0.254	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 825 associations by consensus.

MIR4762 by DNM1P47 expression — THYM

Explore this box plot interactively →