DNM1P33

Across TCGA patient cohorts, DNM1P33 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,879 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DNM1P33-associated GO terms across cancer lineages are Negative regulation of cell cycle G1/S phase transition, Phosphatidylinositol-3-phosphate biosynthetic process, and Obsolete cellular response to extracellular stimulus. Each is linked with DNM1P33 in more than 24 cancer types. Because this analysis shows association rather than direction, both DNM1P33-to-partner and partner-to-DNM1P33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle G1/S phase transition grouped by DNM1P33-low versus DNM1P33-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNM1P33→partner) and Y-score (partner→DNM1P33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of cell cycle G1/S phase transition →	+0.061	+0.237	<.001	.001	3	25
STAD	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.059	+0.251	<.001	<.001	3	24
ESCA	Obsolete cellular response to extracellular stimulus →	+0.055	+0.299	<.001	<.001	3	24
ESCA	Regulation of post-translational protein modification →	+0.063	+0.268	<.001	<.001	3	24
STAD	Regulation of cell cycle G1/S phase transition →	+0.045	+0.297	<.001	<.001	3	24
STAD	Organelle disassembly →	+0.045	+0.222	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,879 associations by consensus.

Negative regulation of cell cycle G1/S phase transition by DNM1P33 expression — ESCA

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