DNHD1

Across TCGA cell cohorts, DNHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,496 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DNHD1-associated genes across cancer lineages are AKAP13, PGAP4, and ESYT1. Each is linked with DNHD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DNHD1-to-partner and partner-to-DNHD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNHD1 versus AKAP13 in BREAST, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNHD1→partner) and Y-score (partner→DNHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	AKAP13 →	+0.783	+1.164	.003	.003	2	5
OESOPHAGUS	PGAP4 →	+1.852	+1.580	.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	ESYT1 →	+0.691	+2.043	.008	<.001	3	4
BLOOD_Myeloma	TGIF1 →	+3.061	+1.540	.002	.005	3	4
SKIN	LYPD1 →	-2.921	-1.843	.002	<.001	3	4
OVARY	CTHRC1 →	+2.618	+1.917	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,496 associations by consensus.

DNHD1 vs AKAP13 — BREAST

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