DND1

Across TCGA patient cohorts, DND1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DND1-associated genes across cancer lineages are VN1R69P, RN7SL719P, and HBZP1. Each is linked with DND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DND1-to-partner and partner-to-DND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R69P grouped by DND1-low versus DND1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DND1→partner) and Y-score (partner→DND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	VN1R69P →	+0.089	+7.640	<.001	.009	3	1
BLCA	RN7SL719P →	+0.194	+7.640	<.001	.009	3	1
BLCA	HBZP1 →	+0.114	+7.640	<.001	.009	3	1
UCEC	MIR8055 →	+0.857	+3.906	.001	.002	3	1
UCEC	MIR6854 →	+0.316	+4.260	<.001	.007	3	1
BLCA	MIR1911 →	+0.472	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

VN1R69P by DND1 expression — BLCA

Explore this box plot interactively →