DNAL4

Across TCGA patient cohorts, DNAL4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,492 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DNAL4-associated genes across cancer lineages are PPP1R42, CCDC157, and PPIL6. Each is linked with DNAL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both DNAL4-to-partner and partner-to-DNAL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAL4 versus PPP1R42 in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAL4→partner) and Y-score (partner→DNAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R42 →	+1.027	+0.444	<.001	<.001	3	6
UCEC	CCDC157 →	+0.488	+0.377	<.001	<.001	3	6
UCEC	PPIL6 →	+1.283	+0.557	<.001	<.001	3	5
HNSC	IFT27 →	+0.743	+0.491	.005	<.001	2	6
BRCA	ST13 →	+0.485	+0.582	.001	<.001	3	5
OV	PTPN22 →	-0.909	-0.462	.005	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,492 associations by consensus.

DNAL4 vs PPP1R42 — UCEC

Explore this scatter interactively →