DNAL4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,976 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DNAL4-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with DNAL4 in more than 14 cancer types. Because this analysis shows association rather than direction, both DNAL4-to-partner and partner-to-DNAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by DNAL4-low versus DNAL4-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAL4→partner) and Y-score (partner→DNAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYCilium or flagellum-dependent cell motility →-0.093-0.919<.001<.001315
KIDNEYCilium-dependent cell motility →-0.093-0.919<.001<.001315
KIDNEYCilium movement involved in cell motility →-0.099-0.928<.001<.001315
KIDNEYFlagellated sperm motility →-0.108-1.065<.001<.001314
KIDNEYSperm motility →-0.108-1.065<.001<.001314
UPPER_AERODIGESTIVE_TRACTProcess utilizing autophagic mechanism →+0.052+0.990.004.008213
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,976 associations by consensus.

Cilium or flagellum-dependent cell motility by DNAL4 expression — KIDNEY

Box plot of Cilium or flagellum-dependent cell motility in DNAL4-low vs DNAL4-high samples in KIDNEY.

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Exploration