DNAL1

Across TCGA patient cohorts, DNAL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,375 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DNAL1-associated proteins across cancer lineages are YLPM1, RPS6, and CEP41. Each is linked with DNAL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNAL1-to-partner and partner-to-DNAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAL1 versus YLPM1 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAL1→partner) and Y-score (partner→DNAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YLPM1 →	+0.286	+0.395	.001	.002	3	7
GBM	RPS6 →	-0.545	-0.373	<.001	<.001	3	6
OV	CEP41 →	+0.375	+0.615	<.001	.001	3	6
OV	TPPP3 →	+1.133	+0.641	<.001	.001	3	6
BRCA	WDR54 →	+0.454	+0.740	<.001	<.001	3	6
UCEC	CARD9_S460 →	-1.074	-0.579	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,375 associations by consensus.

DNAL1 vs YLPM1 — GBM

Explore this scatter interactively →