DNAL1

Across TCGA patient cohorts, DNAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,976 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DNAL1-associated genes across cancer lineages are BBOF1, SAMD15, and TSNAXIP1. Each is linked with DNAL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DNAL1-to-partner and partner-to-DNAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNAL1 versus BBOF1 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAL1→partner) and Y-score (partner→DNAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BBOF1 →	+1.178	+0.499	<.001	<.001	3	7
BRCA	SAMD15 →	+1.261	+0.544	<.001	<.001	3	6
UCEC	TSNAXIP1 →	+0.972	+0.264	<.001	<.001	3	6
LUAD	ZC2HC1C →	+0.437	+0.331	<.001	<.001	3	6
UCEC	IQUB →	+0.923	+0.281	<.001	<.001	3	6
BRCA	TTC8 →	+0.992	+0.526	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,976 associations by consensus.

DNAL1 vs BBOF1 — BRCA

Explore this scatter interactively →