DNAL1

Across TCGA cell cohorts, DNAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,321 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAL1-associated GO terms across cancer lineages are Vesicle tethering to Golgi, Protein localization to cilium, and Protein localization to ciliary transition zone. Each is linked with DNAL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both DNAL1-to-partner and partner-to-DNAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering to Golgi grouped by DNAL1-low versus DNAL1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAL1→partner) and Y-score (partner→DNAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Vesicle tethering to Golgi →	+0.120	+1.018	.006	.002	3	13
LIVER	Protein localization to cilium →	+0.061	+1.222	.004	<.001	2	14
BREAST	Protein localization to ciliary transition zone →	+0.076	+0.793	.002	.002	3	12
BLOOD_Lymphoma	Monoubiquitinated protein deubiquitination →	+0.094	+0.748	<.001	<.001	3	12
OESOPHAGUS	Regulation of metaphase/anaphase transition of cell cycle →	+0.108	+0.798	<.001	<.001	3	11
URINARY_TRACT	Regulation of mitotic spindle checkpoint →	+0.151	+1.004	.003	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,321 associations by consensus.

Vesicle tethering to Golgi by DNAL1 expression — OESOPHAGUS

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