DNAJC5G

Across TCGA patient cohorts, DNAJC5G mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC5G-associated genes across cancer lineages are Annexin_VII, YB-1, and EGFR_pY1068. Each is linked with DNAJC5G in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC5G-to-partner and partner-to-DNAJC5G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin_VII grouped by DNAJC5G-low versus DNAJC5G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC5G→partner) and Y-score (partner→DNAJC5G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin_VII →	-0.136	-2.700	.030	.006	3	2
SKCM	YB-1 →	+0.356	+3.000	.002	.036	3	1
UCEC	EGFR_pY1068 →	-0.261	-3.459	.020	.005	3	1
UCEC	EGFR →	-0.201	-3.169	.005	.019	3	1
UCEC	A-Raf_pS299 →	-0.174	-2.999	.001	.035	3	1
UCEC	FoxM1 →	+0.368	+3.331	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Annexin_VII by DNAJC5G expression — UCEC

Explore this box plot interactively →