DNAJC5G

Across TCGA pan-cancer cohorts, DNAJC5G RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DNAJC5G data layer compared with 4 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher DNAJC5G RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DNAJC5G expression acts as an unfavorable survival marker, although some lineages such as LUSC and STAD show a favorable association.

BRCA, COAD, and ESCA are the cancer types where DNAJC5G RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.848	0.925	<.001	57	view →
COAD	OS	Quartile	All	0.800	0.910	.001	41	view →
ESCA	DFS	Tertile	IV	0.143	0.704	.024	25	view →
LUSC	OS	Quartile	All	0.494	0.329	.005	20	view →
LUAD	OS	Tertile	III,IV	0.419	0.719	.007	18	view →
KIRC	DFS	Tertile	All	0.561	0.698	.012	16	view →
STAD	OS	Median	IV	0.642	0.194	.003	15	view →
MESO	DFS	Quartile	IV	0.329	0.902	.010	15	view →
PAAD	OS	Median	All	0.515	0.250	.007	13	view →
LIHC	OS	Tertile	III,IV	0.285	0.571	.020	8	view →
UCS	DFS	Tertile	II,III,IV	0.537	0.176	.044	8	view →
ACC	OS	Median	IV	0.344	0.724	.038	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

DNAJC5G–BRCA (DFS)

Open the BRCA breakdown →