DNAJC5G

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNAJC5G mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC5G-associated genes across cancer lineages are OR1L6, KCNA4, and KRTAP21-2. Each is linked with DNAJC5G in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC5G-to-partner and partner-to-DNAJC5G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by DNAJC5G-low versus DNAJC5G-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC5G→partner) and Y-score (partner→DNAJC5G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR1L6 →+0.022+4.437<.001.00431
BLOOD_LeukemiaKCNA4 →+0.028+4.922<.001.00931
BLOOD_LeukemiaKRTAP21-2 →+0.085+5.539<.001.00331
BLOOD_LeukemiaFAM24A →+0.082+5.969<.001.00131
BLOOD_LeukemiaIQCF5 →+0.135+5.201<.001.00631
BLOOD_LeukemiaTLE7 →+0.042+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR1L6 by DNAJC5G expression — LARGE_INTESTINE

Box plot of OR1L6 in DNAJC5G-low vs DNAJC5G-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration