DNAJC5B

Across TCGA cell cohorts, DNAJC5B RNA expression is significantly associated with the go_rna of many other GO terms, with 900 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC5B-associated GO terms across cancer lineages are Regulation of postsynaptic density organization, Secretion by tissue, and Regulation of mesenchymal cell proliferation. Each is linked with DNAJC5B in more than 3 cancer types. Because this analysis shows association rather than direction, both DNAJC5B-to-partner and partner-to-DNAJC5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of postsynaptic density organization grouped by DNAJC5B-low versus DNAJC5B-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC5B→partner) and Y-score (partner→DNAJC5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of postsynaptic density organization →	-0.054	-0.103	.001	.002	2	4
CNS	Secretion by tissue →	-0.072	-0.117	.009	.008	3	3
LUNG_SCLC	Regulation of mesenchymal cell proliferation →	-0.113	-0.352	.001	.005	3	3
BLOOD_Leukemia	Anterior commissure morphogenesis →	-0.590	-0.702	.001	.001	3	3
BLOOD_Leukemia	Positive regulation of amino acid transport →	-0.070	-0.565	.001	.008	3	3
BLOOD_Leukemia	Hexose transmembrane transport →	+0.051	+0.525	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 900 associations by consensus.

Regulation of postsynaptic density organization by DNAJC5B expression — CNS

Explore this box plot interactively →