DNAJC5B

Across TCGA cell cohorts, DNAJC5B mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DNAJC5B-associated genes across cancer lineages are LGI1, USP29, and KRT71. Each is linked with DNAJC5B in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC5B-to-partner and partner-to-DNAJC5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGI1 grouped by DNAJC5B-low versus DNAJC5B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC5B→partner) and Y-score (partner→DNAJC5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LGI1 →	+0.122	+5.539	<.001	.003	3	1
BLOOD_Leukemia	USP29 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRT71 →	+0.066	+4.922	<.001	.009	3	1
BLOOD_Leukemia	MCHR2 →	+0.046	+5.539	<.001	.003	3	1
BLOOD_Leukemia	GPR26 →	+0.077	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.144	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

LGI1 by DNAJC5B expression — BLOOD_Leukemia

Explore this box plot interactively →