DNAJC28

Across TCGA cell cohorts, DNAJC28 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DNAJC28-associated genes across cancer lineages are CCL21, KRTAP5-5, and CYP2A13. Each is linked with DNAJC28 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC28-to-partner and partner-to-DNAJC28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL21 grouped by DNAJC28-low versus DNAJC28-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC28→partner) and Y-score (partner→DNAJC28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCL21 →	+0.089	+4.044	<.001	.003	3	1
CNS	KRTAP5-5 →	+0.014	+4.772	<.001	.002	3	1
CNS	CYP2A13 →	+0.034	+4.044	<.001	.003	3	1
CNS	PRB3 →	+0.082	+3.774	<.001	.008	3	1
CNS	DUXA →	+0.040	+3.874	.006	.006	3	1
LARGE_INTESTINE	SH3GL2 →	+1.084	+3.252	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CCL21 by DNAJC28 expression — CNS

Explore this box plot interactively →