DNAJC27

Across TCGA pan-cancer cohorts, DNAJC27 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated DNAJC27 data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DNAJC27 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DNAJC27 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

KIRC, SCLC, and LUAD are the cancer types where DNAJC27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.728	0.546	<.001	89	view →
SCLC	OS	Tertile	All	0.573	0.267	.002	46	view →
LUAD	OS	Median	All	0.857	0.768	.001	45	view →
SKCM	DFS	Quartile	All	0.686	0.540	.002	43	view →
UCS	DFS	Tertile	IV	0.978	0.403	.024	38	view →
PAAD	OS	Quartile	All	0.737	0.407	.001	35	view →
MESO	DFS	Quartile	All	0.525	0.269	.002	28	view →
HNSC	OS	Median	All	0.442	0.334	.010	19	view →
UVM	DFS	Quartile	III,IV	0.222	0.735	.018	17	view →
READ	OS	Median	IV	0.878	0.473	.001	15	view →
ACC	DFS	Quartile	All	0.321	0.795	.001	12	view →
STAD	DFS	Quartile	IV	0.162	0.568	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

DNAJC27–KIRC (OS)

Open the KIRC breakdown →