DNAJC25

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DNAJC25 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC25-associated genes across cancer lineages are Mesangial cells, Sebocytes, and Endothelial cells. Each is linked with DNAJC25 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC25-to-partner and partner-to-DNAJC25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by DNAJC25-low versus DNAJC25-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC25→partner) and Y-score (partner→DNAJC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMesangial cells →-0.051-2.989.022.03731
UCECSebocytes →-0.029-2.978.040.03731
UCECEndothelial cells →-0.045-2.957.042.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Mesangial cells by DNAJC25 expression — UCEC

Box plot of Mesangial cells in DNAJC25-low vs DNAJC25-high samples in UCEC.

Explore this box plot interactively →

Exploration