DNAJC25

Across TCGA cell cohorts, DNAJC25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,495 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DNAJC25-associated GO terms across cancer lineages are Protein targeting to lysosome involved in chaperone-mediated autophagy, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Golgi vesicle transport. Each is linked with DNAJC25 in more than 12 cancer types. Because this analysis shows association rather than direction, both DNAJC25-to-partner and partner-to-DNAJC25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to lysosome involved in chaperone-mediated autophagy grouped by DNAJC25-low versus DNAJC25-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC25→partner) and Y-score (partner→DNAJC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.180	+0.798	.001	<.001	3	12
LIVER	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.104	+0.868	<.001	<.001	2	13
STOMACH	Golgi vesicle transport →	+0.062	+0.799	<.001	<.001	3	11
STOMACH	Protein deubiquitination →	+0.039	+0.712	.009	.003	3	10
BONE	Protein targeting to vacuole involved in autophagy →	+0.211	+0.726	<.001	.003	3	10
BONE	Endoplasmic reticulum organization →	+0.092	+0.727	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,495 associations by consensus.

Protein targeting to lysosome involved in chaperone-mediated autophagy by DNAJC25 expression — STOMACH

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