DNAJC25-GNG10

Across TCGA pan-cancer cohorts, DNAJC25-GNG10 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated DNAJC25-GNG10 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher DNAJC25-GNG10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DNAJC25-GNG10 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUSC show a favorable association.

KICH, DLBC, and LUAD are the cancer types where DNAJC25-GNG10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	All	0.874	0.983	<.001	81	view →
DLBC	OS	Tertile	All	0.398	1.000	<.001	60	view →
LUAD	DFS	Tertile	II,III,IV	0.335	0.579	.002	44	view →
PAAD	OS	Quartile	All	0.684	0.365	.002	36	view →
LUSC	DFS	Tertile	II,III,IV	0.807	0.673	.007	24	view →
COAD	DFS	Quartile	II,III,IV	0.502	0.684	.015	22	view →
SKCM	OS	Quartile	II,III,IV	0.832	0.704	.025	21	view →
THYM	OS	Tertile	II,III,IV	0.689	0.969	.009	12	view →
TGCT	DFS	Tertile	All	0.728	0.860	.036	12	view →
ESCA	DFS	Tertile	All	1.000	0.478	.044	9	view →
READ	DFS	Tertile	IV	0.514	0.636	.008	9	view →
UCS	DFS	Median	IV	0.903	0.505	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

DNAJC25-GNG10–KICH (OS)

Open the KICH breakdown →