DNAJC24

Across TCGA patient cohorts, DNAJC24 mutation is significantly associated with the RNA expression of many other genes, with 1,645 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC24-associated genes across cancer lineages are RNA5SP405, PGBD4P2, and YTHDF3-AS1. Each is linked with DNAJC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC24-to-partner and partner-to-DNAJC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP405 grouped by DNAJC24-low versus DNAJC24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC24→partner) and Y-score (partner→DNAJC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP405 →	+0.347	+3.466	<.001	.003	3	2
READ	PGBD4P2 →	+0.121	+5.257	<.001	.002	3	1
UCEC	YTHDF3-AS1 →	+0.720	+2.860	<.001	.001	3	1
UCEC	HSPE1-MOB4 →	+0.144	+1.984	.005	.007	3	1
UCEC	COPS8P1 →	+0.102	+2.427	<.001	.002	3	1
UCEC	CCL5 →	+1.031	+2.828	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,645 associations by consensus.

RNA5SP405 by DNAJC24 expression — UCEC

Explore this box plot interactively →