DNAJC18

Across TCGA patient cohorts, DNAJC18 mutation is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJC18-associated genes across cancer lineages are CAMTA1-AS2, RPL35P6, and TRGV6. Each is linked with DNAJC18 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJC18-to-partner and partner-to-DNAJC18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMTA1-AS2 grouped by DNAJC18-low versus DNAJC18-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJC18→partner) and Y-score (partner→DNAJC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CAMTA1-AS2 →	+0.079	+3.402	<.001	.007	3	2
SKCM	RPL35P6 →	+0.361	+3.777	.001	.003	3	2
COAD	TRGV6 →	+0.321	+3.958	.002	.006	3	2
UCEC	RNU6-99P →	+0.148	+4.601	<.001	.003	3	2
UCEC	RNU2-47P →	+0.115	+4.601	<.001	.003	3	2
UCEC	TRDV3 →	+0.309	+2.346	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

CAMTA1-AS2 by DNAJC18 expression — SKCM

Explore this box plot interactively →